http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111346098-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-127 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P17-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-7023 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-5517 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-20 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-5517 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P17-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-127 |
| filingDate | 2018-12-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2022-05-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2022-05-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-111346098-B |
| titleOfInvention | Benzodiazepine compound local pharmaceutical composition and preparation method and use thereof |
| abstract | The invention discloses benzodiazepine A topical pharmaceutical composition of a compound of the class comprising a benzodiazepine of formula (I) A compound or a pharmaceutically acceptable salt thereof, a macromolecular dispersion carrier material, a hot-melt protective agent and an optional fluxing agent, wherein R in the formula (I) 1 And R 2 The definition of (A) is detailed in the specification, the topical pharmaceutical composition is administered transdermally by external application to the skin; the method of preparing the topical composition comprises adding the benzodiazepine Micronizing the compound, the high-molecular dispersion carrier material and the hot-melt protective agent, optionally adding a fluxing agent, uniformly mixing to obtain a physical mixture, hot-melt extruding and micronizing to obtain the benzodiazepine The compound particles are prepared. Also provides the application of the pharmaceutical composition. The pharmaceutical composition can be used for calming heart, tranquilizing mind, inducing sleep, improving sleep quality, refreshing brain after use, and has no residue and accumulation in body,the next day of work is not affected and the spirit is full. |
| priorityDate | 2018-12-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 103.