http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111346064-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-5377 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P7-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-2059 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-2095 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-5377 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P7-02 |
| filingDate | 2020-03-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2022-03-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2022-03-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-111346064-B |
| titleOfInvention | Rivaroxaban tablet and preparation method thereof |
| abstract | The invention discloses a rivaroxaban tablet and a preparation method thereof, and belongs to the technical field of pharmaceutical preparations. The preparation method comprises the step of carrying out wet granulation on the rivaroxaban-containing composition by using a hot-melt extruder, wherein the hot-melt extruder is additionally provided with a liquid adding port at a second station, and the rivaroxaban is micronized. In addition, the technological process and parameters for realizing rivaroxaban wet granulation by using the hot-melt extrusion granulator are optimized. The invention extends the function of the hot-melting extrusion granulator, solves the problems of severe process, complex production process and the like of the traditional batch method medicine preparation process, realizes continuous production, and reduces the content uniformity of finished products and the difference between batches of dissolution behaviors. |
| priorityDate | 2020-03-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 37.