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http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N21-33
filingDate 2020-02-24-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2022-11-01-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2022-11-01-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-111337462-B
titleOfInvention A kind of silver nanoparticle fluorescent switch system and preparation method thereof and application in drug detection
abstract The present invention relates to a silver nanoparticle fluorescent switch system, a preparation method thereof, and application in drug detection, comprising silver nanoparticle and fluorescent donor molecule, wherein the silver nanoparticle is surface-modified with specific binding to the drug to be detected. For antibodies, the fluorescence emission spectrum of the fluorescent donor molecule overlaps the UV-Vis absorption spectrum of the silver nanoparticles. Compared with the prior art, the present invention successfully constructs a fluorescence resonance energy transfer system for detecting drugs by selecting suitable donor molecules and acceptor molecules. When the system is used to detect drugs, the background interference is smaller and more reliable. Higher, higher sensitivity and selectivity.
priorityDate 2020-02-24-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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