http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111323588-B
Outgoing Links
Predicate | Object |
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classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-57488 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-543 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-57407 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-543 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-574 |
filingDate | 2020-02-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2020-09-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2020-09-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-111323588-B |
titleOfInvention | Application of esophageal cancer related antigen-protein combination or specific antibody thereof in esophageal cancer detection kit |
abstract | The invention belongs to the fields of molecular biology and oncology, and particularly discloses application of tumor-associated antigens RECK protein, RFT2 protein, PTCH1 protein, NOTCH1 protein, FAT4 protein, AJUBA protein, P53 protein and YAP1 protein in preparation of an esophageal cancer detection kit, particularly application of the protein in preparation of an early-stage esophageal cancer screening detection kit, so that the detection efficiency and the diagnosis efficiency of clinical esophageal cancer are greatly improved, and the protein is favorable for wide popularization and application in common laboratories. The 8 proteins applied to the ELISA kit can simultaneously detect the expression levels of 8 TAA antibodies in serum samples, and has high detection success rate and good technical reproducibility. Correspondingly, the molecule capable of specifically detecting the expression level of the combination of RECK, RFT2, PTCH1, NOTCH1, FAT4, AJUBA, P53 and YAP1 can also be used as an esophageal cancer detection reagent, is applied to an esophageal cancer detection kit, and also has high specificity and sensitivity. |
priorityDate | 2020-02-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 55.