| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_aba919a772df92cccc656ce434ce0660 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2800-107
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2227-106
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2267-0312
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2750-14143
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2217-075 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K67-0276
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-907
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-86
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-4711 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-864
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-90
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01K67-027 |
| filingDate |
2019-12-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0ea78c6a886a8c259a3233fbc481d92f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_31b574f4e5dac934f16cba8620a5bf79
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_36380f46532bdadc9b5c6ae08b8fde48
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0457b48370b22434bdfbc9b94a9704e1
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5000f9c1e4775c824858d37dcb854e27 |
| publicationDate |
2020-06-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CN-111304257-A |
| titleOfInvention |
A method for gene editing by injecting viruses into specific brain regions of animals based on the PSEN1 gene for non-therapeutic purposes |
| abstract |
The invention discloses a method for injecting a virus into a specific brain region of an animal for gene editing based on the non-therapeutic purpose of PSEN1 gene, and using a brain stereotaxic injection pump to directly inject the virus into the specific brain region of a non-human primate; The injection volume was 1 uL of virus per 1 m 3 , and the titer of the injected virus was 10*10 13 vg/mL. This method directly injects viruses into specific brain regions of non-human primates for gene editing, which can obtain transgenic monkey models with disease phenotypes in a short time, and solve the urgent research needs of Alzheimer's disease (AD) at this stage. . |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111304245-A |
| priorityDate |
2018-12-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |