http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111304148-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2500-38 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2500-05 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-15 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-415 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-405 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2506-45 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0602 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-071 |
| filingDate | 2019-12-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2021-04-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2021-04-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-111304148-B |
| titleOfInvention | Application of thiamine in promoting differentiation of human pluripotent stem cells to definitive endoderm cells |
| abstract | The invention discloses application of thiamine in promoting differentiation of human pluripotent stem cells to definitive endoderm cells. Further disclosed is a culture medium for differentiation of human pluripotent stem cells into definitive endoderm cells, the culture medium comprising basal medium, thiamine, a growth factor and a small molecule compound. The invention also provides a method for promoting the differentiation of the human pluripotent stem cells to definitive endoderm cells. The invention discovers for the first time that thiamine can greatly improve the efficiency and purity of inducing differentiation of human pluripotent stem cells to obtain definitive endoderm cells, improves the differentiation efficiency from 55-79% to 94-98%, and provides good cell resources for downstream differentiation of the definitive endoderm cells. |
| priorityDate | 2019-12-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 90.