http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111303087-B

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classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D307-60
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D307-68
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D307-60
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D307-68
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-341
filingDate 2020-04-07-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2021-08-10-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2021-08-10-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-111303087-B
titleOfInvention Furanone compound and preparation method and application thereof
abstract The invention discloses furanone compounds and a preparation method and application thereof. The p-hydroxybenzaldehyde and halogenated isoamylene are alkylated, and then are protected by benzyl to obtain a benzaldehyde derivative intermediate. The benzaldehyde derivative intermediate and phenylpyruvic acid ester intermediate are subjected to aldol condensation and molecular lactonization under the catalysis of a condensing agent to synthesize novel furanone compounds BL5 and BL 10. The furanone derivative has H1N1 virus inhibitory activity, and can be used for preparing medicines for treating H1N1 virus infection.
priorityDate 2020-04-07-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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