http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111303087-B
Outgoing Links
Predicate | Object |
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classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D307-60 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D307-68 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D307-60 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D307-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-341 |
filingDate | 2020-04-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2021-08-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2021-08-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-111303087-B |
titleOfInvention | Furanone compound and preparation method and application thereof |
abstract | The invention discloses furanone compounds and a preparation method and application thereof. The p-hydroxybenzaldehyde and halogenated isoamylene are alkylated, and then are protected by benzyl to obtain a benzaldehyde derivative intermediate. The benzaldehyde derivative intermediate and phenylpyruvic acid ester intermediate are subjected to aldol condensation and molecular lactonization under the catalysis of a condensing agent to synthesize novel furanone compounds BL5 and BL 10. The furanone derivative has H1N1 virus inhibitory activity, and can be used for preparing medicines for treating H1N1 virus infection. |
priorityDate | 2020-04-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 76.