http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111269280-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H15-203 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C233-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-44 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H15-203 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C233-18 |
| filingDate | 2020-03-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2021-07-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2021-07-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-111269280-B |
| titleOfInvention | Compound, corresponding internal standard and kit for detecting enzyme related to lysosomal storage disease |
| abstract | The invention discloses a compound, a corresponding internal standard and a kit for detecting enzymes related to lysosomal storage diseases. The compound has a structure shown as the following formula I: the lysosomal storage disease-associated enzyme comprises one or more of acid β -glucocerebrosidase, β -galactocerebroside, α -galactosidase, and acid α -glucosidase. The compound for detecting the enzyme related to the lysosomal storage disease, provided by the invention, has the structure that the part for connecting the glucoside and the ammonia alcohol contains the benzene ring and the benzene ring is connected with the end part of the ammonia alcohol through an ester bond, so that the contact flexibility of the substrate and the related enzyme is improved, and the combination efficiency of the enzyme and the substrate can be improved. In addition, the invention preferably combines R1 and R2 to improve the specificity of detection and increase the detection sensitivity. |
| priorityDate | 2020-03-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 126.