http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111269247-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02A50-30 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D513-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-542 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-542 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D513-04 |
| filingDate | 2020-03-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2020-11-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2020-11-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-111269247-B |
| titleOfInvention | Preparation method of buprofezin drug molecule with escherichia coli inhibition effect |
| abstract | The invention discloses a preparation method of buprofezin drug molecules with an escherichia coli inhibition effect, and belongs to the technical field of drug synthesis. The technical scheme provided by the invention has the key points that: the buprofezin drug molecule has a structure Wherein R is a urea structure or a 1,2, 3-triazole structure. According to the invention, 3-carbonyl-4- (4-methylphenyl) butyronitrile is used as a raw material, and the buprofezin target compound can be obtained through four-step reaction, so that the reaction operation is simple and the yield is high; hydroxyl obtained by forming an enol structure by using the ketocarbonyl at the 8 th position in the target compound can better form acting force with amino acid in escherichia coli, and further has good effect of inhibiting the escherichia coli. |
| priorityDate | 2020-03-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 108.