| abstract |
The invention discloses a 3D printed skin and a preparation method thereof, wherein the skin consists of an artificial epidermis layer, an acellular dermis bracket and an artificial dermis layer from top to bottom, and is characterized in that the skin is prepared by performing two-component 3D printing on polyamino acid hydrogel and hyaluronic acid hydrogel. Compared with the prior art, the invention has the following advantages: (1) this skin adopts the compound shaping of printing of bi-component material, and the shaping is fast, and the external shower nozzle of heliciform that adopts has further reduced the fashioned time of printing, and it is difficult for collapsing and shape retentivity good to print the in-process. (2) The appropriate shape, size and pore structure determined by scanning are adopted, and a decellularized dermal scaffold is added, so that the cell ingrowth and wound healing are facilitated, and a certain degree of mechanical support is provided. |