http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111265529-B
Outgoing Links
Predicate | Object |
---|---|
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P17-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-497 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P17-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-497 |
filingDate | 2020-02-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2021-07-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2021-07-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-111265529-B |
titleOfInvention | Application of protein tyrosine phosphatase SHP2 inhibitor in preparation of medicine for treating psoriasis |
abstract | The invention belongs to the technical field of pharmacy. The application of a protein tyrosine phosphatase SHP2 inhibitor SHP099 in preparation of a medicament for treating psoriasis aims at an imiquimod-induced psoriasis-like disease model of a mouse, and the SHP099 can effectively improve epidermal thickening, inflammatory cell infiltration and the level of inflammatory factors in serum of the mouse. At the cellular level, SHP099 significantly reduced the release of inflammatory factors associated with psoriasis. |
priorityDate | 2020-02-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 101.