http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111265503-B
Outgoing Links
Predicate | Object |
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classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-01 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P17-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P5-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P13-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P17-14 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P13-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P17-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P17-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-01 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P5-28 |
filingDate | 2020-03-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2021-03-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2021-03-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-111265503-B |
titleOfInvention | Composition for inhibiting activity of 5 alpha-reductase and application thereof |
abstract | The invention discloses a composition for inhibiting 5 alpha-reductase activity. The composition comprises lycopene, curcumin and ar-turmerone. Researches show that compared with a single plant extract and a model control group, the composition disclosed by the invention can obviously inhibit the activity of 5 alpha-reductase, reduce the content of dihydrotestosterone in animal tissues and serum, also can obviously induce the activity reduction of benign hyperplastic cells of human prostatic stroma and human prostatic hyperplastic epithelial cells, obviously inhibit the proliferation of human sebaceous gland cells and obviously promote the proliferation of human papillary dermal cells, and has an obvious synergistic effect on the prevention and treatment of androgen diseases such as prostate diseases, androgenetic alopecia or acne and the like. The plant extract composition provided by the invention is efficient and has no toxic or side effect, and has important application value for preventing and treating androgen diseases. |
priorityDate | 2020-03-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 60.