http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111264516-B

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classificationCPCAdditional http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2523-00
classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0691
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filingDate 2020-02-20-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2020-10-30-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2020-10-30-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-111264516-B
titleOfInvention Cryo-free blood vessel preservation solution and blood vessel preservation method
abstract The invention discloses a blood vessel ice-free cryopreservation liquid and a blood vessel preservation method, wherein the blood vessel ice-free cryopreservation liquid comprises 1.0-6.0mol/L of glycerol, 1.0-7.0mol/L of formamide, 0.1-2.5mol/L of polyvinylpyrrolidone and a component X; the component X is one or more of a component A, a component B or a component C; wherein component A is NO donor, component B is endothelin inhibitor or endothelin antagonist, and component C is anti-apoptosis agent. The preservation solution provided by the invention improves the preservation effect on the functions of blood vessels, particularly can effectively protect blood vessel smooth muscle cells and endothelial cells which are most easily damaged by freezing, has the function of effectively protecting the blood vessel smooth muscle cells and the endothelial cells, improves the long-term patency rate after blood vessel transplantation, and greatly ensures the success rate of clinical transplantation of the blood vessels.
priorityDate 2020-02-20-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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