http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111253935-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C09K2211-1007 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C09K2211-1037 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C09K2211-1029 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-6428 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C09K11-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D417-06 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D417-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N21-64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C09K11-06 |
| filingDate | 2019-12-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2022-12-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2022-12-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-111253935-B |
| titleOfInvention | A two-photon fluorescent probe for dual-channel detection of polarity and viscosity, its preparation method and use |
| abstract | The invention discloses a two-photon fluorescent probe for detecting polarity and viscosity with two channels and its preparation method and application, which can monitor the real-time changes of polarity and viscosity in cell mitochondria in two different channels at the same time, and its structural formula is as follows: The two-photon fluorescent probe molecule of the present invention can utilize two different fluorescent wavebands to simultaneously respond fluorescently to polarity (short wave, 410nm) and viscosity (long wave, 580nm). In addition, the cytotoxicity test shows that the probe has almost no toxic side effects on the cells, and the two-photon confocal fluorescence microscopy imaging experiment shows that the probe has good permeability to HeLa cells and can effectively locate the mitochondria in the cells (the localization coefficient is 0.97). , for dual-channel two-photon fluorescence imaging and detection of polarity and viscosity within cell mitochondria. |
| priorityDate | 2019-12-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 43.