http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111253415-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D493-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D493-18 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D493-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D493-08 |
| filingDate | 2020-03-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2022-08-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2022-08-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-111253415-B |
| titleOfInvention | Norcantharidin carboxylate trifluorobenzyl ester and its synthesis method and application |
| abstract | Norcantharidin carboxylate trifluorobenzyl ester, its structural formula is shown in formula I The specific structure of norcantharidin carboxylate trifluorobenzyl shown in formula I includes: The activity test shows that the trifluorobenzyl norcantharidin carboxylate as shown in I synthesized by the present invention is a suitable anti-tumor drug candidate, especially as a candidate drug against liver cancer. Compared with the positive control drugs norcantharidin and norcantharidin sodium, the water solubility, stability and antitumor activity are improved. In addition, the method for synthesizing trifluorobenzyl norcantharidin carboxylate of the present invention has easily available raw materials and is very easy to operate and implement. |
| priorityDate | 2020-03-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 36.