| abstract |
The invention relates to a medical material, in particular to the field of cartilage injury regeneration, and mainly discloses a bionic multilayer collagen scaffold for cartilage repair and a preparation method thereof. The scaffold product has a multilayer three-dimensional space structure, promotes in-vivo cell recruitment by reducing the immunogenicity of materials and adopting a multilayer overlapping design of a compact layer, a porous layer and a barrier layer, realizes in-vivo cartilage regeneration induced by a biomaterial without exogenous cells, optimizes a regeneration strategy, and is suitable for the treatment and regeneration of cartilage injury. |