http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111235106-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2510-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-16 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0636 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-115 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-0011 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-0783 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-115 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
| filingDate | 2020-03-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2022-08-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2022-08-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-111235106-B |
| titleOfInvention | A kind of Aptamer-CD3+ T cell targeting tumor cells and its construction method and application |
| abstract | The invention discloses an Aptamer-CD3 + T cell targeting tumor cells and a construction method and application thereof. It belongs to the technical field of tumor immune adoptive therapy. Specifically, the specific target-recognizing tumor cell aptamer (aptamer) is coupled to CD3 + T cells using glucose metabolism pathways and bioorthogonal reactions to prepare Aptamer-CD3 + T cells that can target and recognize tumor cells. Using the Aptamer‑CD3 + T cells as a drug, it can be used to target and inhibit tumor cell growth in vitro and in vivo. The invention provides a new technical method for the preparation of tumor immunotherapy cells. |
| priorityDate | 2019-08-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 78.