| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b4711b7defc1422cdb7f86d2c95657bf |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C09K2211-1029 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-59
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C09B23-086
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-0056
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C09K11-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-0034 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-59
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K49-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-113
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C09B23-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C09K11-06 |
| filingDate |
2020-01-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bb447f76d70fed1ea9de07c26a93b965
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e29086ecc3e661cd8617490a28191000
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3f27c569a53f5751779e67224a47a46c |
| publicationDate |
2020-06-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CN-111234813-A |
| titleOfInvention |
Follicular granulosa cell near-infrared fluorescent probe Nirova-1 and its preparation method and application |
| abstract |
The invention belongs to the technical field of medical imaging contrast agents, in particular to a near-infrared fluorescent probe Nirova-1 of a living ovarian follicle and a preparation method and application thereof. The fluorescent probe of the invention is a fluorescent dye-human follicle-stimulating hormone complex formed by coupling organic small molecule indocyanine green (ICG) and human follicle-stimulating hormone (FSH); the complex enables the fluorescent dye to specifically target the ovary The structure of the follicles in the follicles enables near-infrared fluorescent labeling of all follicles. The fluorescent probe combines the characteristics of ICG's fluorescence emission in the near-infrared region and the specific targeting and binding properties of FSH to granulosa cells in the ovary. and developmental stage for accurate and effective detection and evaluation. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112442117-B
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112442117-A |
| priorityDate |
2020-01-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |