http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111233880-B

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http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-0021
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http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N21-64
filingDate 2020-02-28-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2022-08-23-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2022-08-23-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-111233880-B
titleOfInvention A kind of preparation method of hypochlorite fluorescent probe
abstract The invention belongs to the technical field of fluorescent probes, and particularly relates to a preparation method of a hypochlorite fluorescent probe. The invention provides 8-hydroxyjulonidine-9-aldehyde as a starting material, and the fluorescent probe is synthesized by the generated coumarin 343 acid chloride and 2,4-dinitrophenylhydrazine under the action of triethylamine preparation method; the fluorescent probe is a hypochlorite fluorescent probe with extremely low background fluorescence and high sensitivity, which can selectively identify hypochlorite, and as the concentration of hypochlorite increases, its fluorescence intensity is at 488nm Gradually enhanced; the probe has the function of sensitive and rapid identification; the fluorescent probe prepared by the invention can be used for the detection of hypochlorite content in actual water samples, the detection of exogenous/endogenous hypochlorite in living cells and the detection of zebrafish Detection of hypochlorite in vivo.
priorityDate 2020-02-28-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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Total number of triples: 31.