http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111228217-B
Outgoing Links
Predicate | Object |
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classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-1075 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P7-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4365 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0019 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4365 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P7-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-107 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-44 |
filingDate | 2020-02-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2022-02-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2022-02-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-111228217-B |
titleOfInvention | Submicron emulsion containing clopidogrel or phospholipid complex of clopidogrel salt and preparation method thereof |
abstract | The invention belongs to the field of medicines, and discloses a submicron emulsion containing a phospholipid complex of clopidogrel or clopidogrel salt, which comprises the following components: phospholipid complex, vegetable oil, emulsifier, solubilizer, stabilizer, pH regulator and water; the phospholipid complex is prepared by the following method: dissolving clopidogrel and/or clopidogrel salt and phospholipid in an organic solvent, reacting, and removing the organic solvent to obtain the phospholipid complex. The invention utilizes clopidogrel and/or clopidogrel salt and phospholipid to form phospholipid complex, then prepares submicron emulsion, can be directly injected to patients, and after entering blood, the concentration of clopidogrel and/or clopidogrel salt rises rapidly, thus being capable of treating patients rapidly; the clopidogrel and/or clopidogrel salt and phospholipid are utilized to form a phospholipid complex, so that the stability of the clopidogrel and/or clopidogrel salt is improved, and the overall stability of the submicron emulsion is also improved. |
priorityDate | 2020-02-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 70.