http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111217862-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-584 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F17-02 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F17-02 |
| filingDate | 2020-02-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2023-01-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2023-01-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-111217862-B |
| titleOfInvention | A kind of preparation method of 4-aryl-6-ferrocenyl-3,4-dihydropyrimidin-2(1H)-one |
| abstract | The invention discloses a method for preparing 4-aryl-6-ferrocenyl-3,4-dihydropyrimidin-2(1H)-one. Add A mol of choline chloride and B mol of urea to a dry three-necked flask, stir at 80°C to obtain a deep eutectic solvent, then add C mol of acetylferrocene, D mol of urea, Emol of aromatic aldehyde, Fmol of Lewis acid , reacted at 80°C, and monitored by TLC until the reaction was complete. After the reaction is over, the reaction mixture is poured into water to precipitate a solid, which is suction filtered and washed with water to obtain the product. The filtrate can be recycled to obtain the deep eutectic solvent. The present invention does not need organic solvents, simple operation, high yield, high product purity, short reaction time, simple post-treatment, and the deep eutectic solvent can be recycled and reused, green and environmentally friendly, low cost, and has great advantages in the synthesis and development of this type of compound. Significance. |
| priorityDate | 2020-02-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 70.