http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111217726-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D495-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C317-44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C315-04 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C317-44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C315-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D495-04 |
| filingDate | 2020-02-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2021-08-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2021-08-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-111217726-B |
| titleOfInvention | Paeonol ester derivative and preparation method and application thereof |
| abstract | The invention discloses a paeonol ester derivative, a preparation method and application thereof, wherein the paeonol ester derivative has the following structural formula: the invention designs potential paeonol derivatives with anti-inflammatory immunocompetence by a molecular docking technology based on molecular targets related to inflammatory diseases, synthesizes the derivatives by a chemical modification means on the basis, and compared with the traditional chemical modification based on improvement of pharmaceutical properties of paeonol, the technical means of the invention has the advantages of high efficiency of obtaining the high-biological-activity paeonol derivatives, stronger anti-inflammatory active drugs than paeonol and similar products, and solves the problems of weak anti-inflammatory immunocompetence, weak water solubility, easy oxidation, volatility and the like of the paeonol. |
| priorityDate | 2020-02-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 90.