| abstract |
The invention relates to a nanoparticle emulsion loaded with a skin nutrient and a preparation method thereof, and is characterized in that: comprises the following components in percentage by weight: 0.1% -50% of spidroin, 0.1% -10% of bis-hydroxyethyl trimethylol methylamine, 0.1% -40% of a skin nutrient and 0.1% -85% of a hydroalcoholic mixture, wherein the molecular weight of the spidroin is 80-100 kDa. The nanoparticle emulsion loaded with the skin nutrient has better biocompatibility, milder property and low irritation; compared with other spider silk protein nano-emulsions, the spider silk protein nano-emulsion has the advantages of higher encapsulation efficiency, better absorption and permeability and better stability. |