| abstract |
The invention provides a qualitative detection method for pioglitazone and rosiglitazone in food and medicine, and belongs to the field of substance detection. The invention adopts the ratio of two gold nanoparticles as the nanoparticle enhancing reagent, and is supplemented with water-saturated chloroform as the extracting agent for extraction without acid, which is safer, reduces interference, and enhances the Raman effect of the target. , at the same concentration, the features are more obvious and the intensity is greater, which can improve the accuracy of the detection results. The data of the examples show that the method of the present invention is suitable for surface-enhanced Raman spectroscopy to detect the illegally added pioglitazone and rosiglitazone in the hypoglycemic health food, and the detection limit of the method is 15 μg/mL. |