http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111208104-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a9e6a0102f7dc0397aaeb636aa13eafb |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2021-6432 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-6428 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-6486 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N21-64 |
| filingDate | 2020-01-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_58356e288d0eb1e096df7a47585d4ebd http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_61125bd4b1ddfb6e2257a983cd735191 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a5abd9d0a53d5f2a005714a9ebdef2ac http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fd5ddae2bc1febdd8cccb529ebbe935a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_296874b52bc6ab720ad49ed947ca9194 |
| publicationDate | 2020-05-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-111208104-A |
| titleOfInvention | Preparation of Fluorescent Polydopamine Nanoparticles with Controllable Size and Detection of Trypsin |
| abstract | The invention discloses the preparation of fluorescent polydopamine nanoparticles with controllable particle size and its use in trypsin detection. It is characterized in that the polydopamine nanoparticles can be decomposed into fluorescent polydopamine nanoparticles with a particle size of less than 5 nm by self-polymerizing dopamine under alkaline conditions, and then adding H 2 O 2 and controlling the time and temperature. . The preparation method of the invention has simple steps, uses green and environment-friendly source materials, and the particle size of the product is controllable. The fluorescent polydopamine nanoparticle of the invention has rich negative charges on its surface and has good fluorescence performance, and quenches the fluorescence through electrostatic adsorption and hydrogen bond aggregation with cationic protamine. The detection of trypsin was achieved based on the recovery of the fluorescence of polydopamine nanoparticles only by a simple mixing operation, and the lowest detection limit of trypsin could reach 6.4 ng/mL. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112326618-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-115594845-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112326618-B http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113150326-A |
| priorityDate | 2020-01-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 53.