http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111205266-A
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5a886effb3e588e6715fedddb2395382 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D333-24 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D333-24 |
filingDate | 2020-01-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9b5325a15e41a0a640d55d36764fac93 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a6e8818ef330910101ed37228746c095 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dca6a8b1c03effa1c64b697c8d080088 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_57786c055859a92cc6095dbd0bcc92cc http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3b4dcc9189f71400468284ee3784531e |
publicationDate | 2020-05-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-111205266-A |
titleOfInvention | A kind of synthetic method of 2-thiopheneacetic acid |
abstract | The invention provides a method for synthesizing 2-thiopheneacetic acid, which is characterized by comprising the following steps: (1) acylation reaction: using thiophene and 2-chloroacetyl chloride as raw materials to obtain 2-chloroacetyl group through Friedel-Crafts reaction thiophene; (2) rearrangement reaction: 2-chloroacetylthiophene undergoes Favorskii rearrangement reaction under alkaline conditions to obtain 2-thiopheneacetic acid. The method has a wide range of raw material sources, low cost, few steps, simple operation, high safety, low pollution, and is easy to realize industrialization. The operation is simple, no special reagents are required, the raw materials are cheap and easy to obtain, the equipment requirements are not high, the product yield is high, the impurities are less, and the method has obvious advantages and practical value. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114605375-B http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114605375-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-115160290-A |
priorityDate | 2020-01-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 119.