http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111202838-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-164 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P11-00 |
| filingDate | 2020-02-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2020-10-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2020-10-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-111202838-B |
| titleOfInvention | Application of flagellin derived polypeptide CBLB502 in prevention and treatment of acute lung injury |
| abstract | The invention discloses application of flagellin derived polypeptide CBLB502 in prevention and treatment of acute lung injury. The invention provides application of CBLB502 protein or related biological materials thereof in preparing products for preventing and/or treating acute lung injury; the related biological material is a nucleic acid molecule capable of expressing the CBLB502 protein or an expression cassette, a recombinant vector, a recombinant bacterium or a transgenic cell line containing the nucleic acid molecule. The research of the invention finds that CBLB502 can obviously reduce the tissue damage degree of the hydrochloric acid inhalation lung damage, and reduce the lung wet-dry ratio, the total cell number and the secretory protein amount in alveolar lavage fluid, and the levels of superoxide dismutase SOD and myeloperoxidase MPO of lung tissues. The results indicate that the CBLB502 can be used for preventing and treating the acute lung injury caused by acid substance inhalation, and provides a new idea and a new medicine for treating chemical lung injury and the like caused by haze. |
| priorityDate | 2020-02-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 287.