http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111202737-B
Outgoing Links
Predicate | Object |
---|---|
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P19-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-56 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-02 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P37-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-56 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P19-02 |
filingDate | 2020-03-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2022-08-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2022-08-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-111202737-B |
titleOfInvention | Application of triptolide amide derivatives in the preparation of drugs for the treatment of autoimmune diseases |
abstract | The invention discloses the use of triptolide amide derivatives represented by formula III or pharmaceutically acceptable salts thereof in preparing medicines for treating autoimmune diseases, wherein R is selected from C1-C6 alkyl groups; Autoimmune diseases are rheumatoid arthritis, systemic lupus erythematosus, and multiple sclerosis. The present invention also discloses a medicine for treating autoimmune diseases, comprising an effective therapeutic dose of triptolide amide derivative or a pharmaceutically acceptable salt thereof and one or more pharmaceutically acceptable excipients. The triptolide amide derivative has high efficiency and low toxicity, can be used as a new type of immunosuppressant with high efficiency and low toxicity, and has the prospect of treating autoimmune diseases, especially rheumatoid arthritis. |
priorityDate | 2020-03-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 116.