http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111197068-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12M23-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0697 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12M21-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5011 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-071 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12M1-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12M3-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-02 |
| filingDate | 2020-01-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2022-04-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2022-04-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-111197068-B |
| titleOfInvention | Method for drug sensitivity test based on super-hydrophobic microarray chip |
| abstract | The invention provides a method for drug sensitivity test based on a super-hydrophobic microarray chip, which comprises the steps of culturing organoids in super-hydrophobic microarray chip micro-pits to obtain organoid cells, adding to-be-tested drugs with different concentrations and fluorescent dye solutions for cell proliferation and/or cell toxicity detection into the micro-pits, detecting the change of the fluorescent value of the fluorescent dye according to the cell proliferation and/or cell toxicity before and after the addition of the to-be-tested drugs with each concentration, and then determining the IC50 value of the to-be-tested drugs on the organoid cells according to the cell viability value of the to-be-tested drugs with each concentration. The invention combines the 3D culture technology with the super-hydrophobic microarray chip, can realize the culture of the organoids from different patients on the whole chip, and simultaneously performs the drug sensitivity test of various drugs on the organoids from one patient, and performs the drug sensitivity test of one or more drugs on the organoids from various patients. |
| priorityDate | 2020-01-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 28.