http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111189808-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2021-6439 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-705 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-085 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-158 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-988 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-96472 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-6428 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6883 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6893 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N15-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-573 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6883 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N15-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N21-64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-573 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68 |
| filingDate | 2019-12-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2022-12-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2022-12-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-111189808-B |
| titleOfInvention | Screening method for specific protein molecular markers related to liver injury and hepatocyte apoptosis |
| abstract | The method for screening protein molecular markers related to liver injury and abnormal apoptosis of hepatocytes comprises the following steps: screening of PSMD10 in liver tissues of CBS mouse control group and experimental group; expression verification of PSMD10 in human liver cells; transfection of PSMD10 interference fragments. Changes of hepatocyte apoptosis proteins cleaved caspase3 and cleaved caspase12 in transfected cells; changes in the apoptosis rate of hepatocytes by PSMD10 interference fragment transfected cells by flow cytometry; detection of ERs in mouse liver tissue; detection of liver function in mouse serum . The present invention establishes a protein target in HHcy-induced liver injury and hepatocyte apoptosis detection composed of PSMD10, cleaved caspase3 and cleaved caspase12. The method is simple, reliable and easy to popularize. |
| priorityDate | 2019-12-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 273.