| abstract |
The invention discloses a collagen-sodium humate compound suitable for a hemostatic material and a preparation method thereof. The invention takes natural collagen with good bioactivity and natural polymer sodium humate with the functions of stopping bleeding and promoting wound healing as main raw materials, prepares a composite solution with good compatibility by virtue of the charge shielding effect of salt under the condition of low temperature, prepares composite hydrogel through collagen self-assembly, and prepares the collagen-sodium humate composite through freeze drying. The prepared composite hydrogel and sponge improve the thermal stability, hemostasis, platelet coagulation promotion and other performances of single collagen hydrogel, and the hydrogel and sponge have the advantages of good porosity, hydrophilicity, antibiosis, anti-inflammatory and the like. The hydrogel and sponge can be used alone or in combination with other materials for hemostatic dressing. |