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filingDate 2018-09-26-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0623a450c65b4b960cd9178821db52c0
publicationDate 2020-05-19-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-111182922-A
titleOfInvention Method for preventing reduction of disulfide bonds in cell culture harvests
abstract The present disclosure relates to a method for preventing reduction of disulfide bonds in a polypeptide expressed in a recombinant host cell, comprising adding phosphate to a harvest solution of the recombinant host cell after fermentation, wherein the disulfide bonds in the polypeptide remain unreduced of.
priorityDate 2017-10-02-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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