http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111170886-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C2603-80 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C249-02 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C251-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C249-02 |
| filingDate | 2020-01-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2021-11-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2021-11-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-111170886-B |
| titleOfInvention | Preparation method of dezocine impurity |
| abstract | The invention discloses a preparation method of dezocine impurities, which adopts (5R,11S,13S) -3-methoxy-5-methyl-5, 6,7,8,9,10,11, 12-octahydro-5, 11-methylene benzocyclodecene-13-amine as a starting raw material to efficiently synthesize and prepare (5R,11S) -3-hydroxy-5-methyl-5, 6,7,8,9,10,11, 12-octahydro-5, 11-methylene benzocyclodecene-13-imine; the preparation method has the advantages of simple operation, easily obtained raw materials, mild reaction conditions, high product purity and high yield, and is suitable for large-scale preparation. The synthesized impurities can be used for qualitative and quantitative analysis of the impurities, so that the medication safety of dezocine can be improved. |
| priorityDate | 2020-01-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 50.