http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111154118-A
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c23d84d2f6dd5c06aea424c9fb3bc340 |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08J2353-00 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08F8-44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08J3-07 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08F293-00 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08J3-07 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08F8-44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08F293-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08L53-00 |
filingDate | 2020-01-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e78653bd7d639c89e181c0ac5a4bf2a0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4f9e051bfea08b9d262f63c2deb0980c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_61e4667671996a29b8b22c2ee5442d50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fc8b2d2b96a3ae4a03361b2ec6eeffa9 |
publicationDate | 2020-05-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-111154118-A |
titleOfInvention | A kind of single crystal polymer micelle with different aspect ratio and preparation method thereof |
abstract | The invention belongs to the technical field of polymer materials, in particular to a single crystal polymer micelle with different aspect ratios and a preparation method thereof, comprising the following steps: (1) synthesis of block polymers, (2) PCL-containing crystallization Synthesis of block ionic amphiphilic block copolymer, (3) Preparation of single crystal polymer micelle: The ionic amphiphilic block copolymer is dissolved in a good solvent and added dropwise at a preset speed Ultrapure water was used to obtain the initial micelle solution; then, the Hofmeister ion sequence solution was added dropwise, and after stirring, single crystal polymer micelles with different aspect ratios were obtained. The preparation method of the invention has the advantages of simple operation, simple process and mild preparation conditions, and can prepare two-dimensional single crystal structure polymer micelles with a size of micrometer in a relatively short time; Large loading capacity; longer in vivo circulation time than zero-dimensional spherical structures when used for in vivo drug delivery. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-115536883-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112626613-A |
priorityDate | 2020-01-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 44.