http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111153883-B
Outgoing Links
Predicate | Object |
---|---|
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D311-76 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-10 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D311-76 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-352 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P3-10 |
filingDate | 2020-01-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2022-04-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2022-04-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-111153883-B |
titleOfInvention | Mixed-element terpenoid Verruculide B4 and preparation method and application thereof |
abstract | The invention relates to the technical field of natural products and medicines, and discloses a mixed terpenoid Verruculide B4, and a preparation method and application thereof. The mixed-element terpenoid Verruculide B4 has a structure shown in a formula (I). In the research process of fungus (Penicillium sp) SCS-KFD09 metabolite, the invention obtains a mixed terpenoid compound Verruculide B4 which has stronger protein tyrosine kinase 1B (PTP1B) inhibition activity and no cytotoxic activity, and is an ideal drug lead compound for developing high-efficiency and low-toxicity anti-type 2 diabetes. |
priorityDate | 2020-01-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 185.