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filingDate 2019-12-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 2020-05-12-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-111138500-A
titleOfInvention Monoiodobenzoic acid-modified Anderson polyacid organic derivative A2 and its application in anti-EV71 virus
abstract The invention provides a monoiodobenzoic acid modified Anderson polyacid organic derivative A2 and its application in anti-EV71 virus. Through the research experiments on the EV71 virus inhibitory activity of the polyiodocarboxylic acid-modified Anderson polyacid organic derivative A1-A3, it was confirmed that the polyiodocarboxylic acid-modified Anderson polyacid organic derivative A2 could inhibit the cytopathic effect caused by EV71 virus. effect, enhance the survival rate of infected cells, and inhibit the replication and proliferation of EV71 virus in cells. The polyiodocarboxylic acid-modified Anderson polyacid organic derivative A2 provided by the present invention has the potential to prepare a specific therapeutic drug against EV71 infection, and has the advantages of good clinical application prospects.
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