http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111134089-B
Outgoing Links
Predicate | Object |
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classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2267-03 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2207-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2227-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2207-12 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K67-027 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61D7-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61D1-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K35-74 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-74 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61D1-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01K67-027 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61D7-00 |
filingDate | 2020-02-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2022-04-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2022-04-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-111134089-B |
titleOfInvention | Method for establishing canine staphylococcus intermedium keratococcus corneal ulcer model |
abstract | The invention belongs to the technical field of biology, and particularly relates to a method for establishing a canine staphylococcus pseudointermedium corneal ulcer model; after the experimental dog is anesthetized, the cornea and the conjunctival sac are washed by povidone iodine solution, the residual povidone iodine solution is washed clean by sodium lactate ringer solution, the eyelid opening device is used for opening the eyelid, the right side of the experimental dog is laid and fixed, the focal length of a microscope and the head position of the experimental dog are adjusted, and the eyeball is ensured to be completely exposed in the visual field; sucking the staphylococcus pseudomediae bacterial liquid, inserting a needle of an injector from the position 0.3mm right of the horizontal line of the center of the pupil under the observation of a microscope, penetrating through the corneal epithelium layer, injecting the bacterial liquid into the corneal stroma layer at the center, pressing the needle inserting point, pulling out the injector, and pressing for a moment; the eyelid retractor is removed and the upper and lower eyelids are closed. The method has the advantages of simple experimental equipment, simple and convenient operation method, good repeatability, no occurrence of undesirable conditions such as concurrent infection and death of experimental dogs, and wide application range, and can successfully construct the canine staphylococcus aureus corneal ulcer model. |
priorityDate | 2020-02-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 245.