| abstract |
A preparation method and application of a polyvinyl alcohol hemostatic porous material with high liquid absorption and high expansion performance and active hemostasis function. The hemostatic sponge prepared by the invention can be used for hemostasis of penetrating wounds and irregular incompressible wounds in emergency situations. The polyvinyl alcohol hemostatic sponge does not use the traditional aldehyde-based cross-linking method, nor does it add a large amount of concentrated acid catalyst, thus avoiding the tedious cleaning steps of post-processing, greatly improving the biological safety of the final product, due to the prepared sponge It has high liquid absorption capacity and swelling performance. When in contact with blood, it can absorb a large amount of water in the blood to concentrate the coagulation components, and it can quickly expand during the liquid absorption process to achieve the effect of compression and hemostasis; at the same time, active hemostatic preparations The addition of the sponge can better improve the coagulation effect of the sponge. The present invention has good biocompatibility, high liquid absorption capacity and swelling performance, and excellent hemostatic effect, etc., and has broad clinical application prospects. |