http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111116662-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F9-65846 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F9-6584 |
| filingDate | 2019-11-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2022-12-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2022-12-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-111116662-B |
| titleOfInvention | A kind of preparation method of fluorinated cyclic phosphonamide derivative |
| abstract | The invention belongs to the technical field of organic synthesis and discloses a preparation method of fluorinated cyclic phosphonamide derivatives. In the preparation method, compound I, compound II, Ag 2 CO 3 , NaHCO 3 , [RhCp*Cl 2 ] 2 , and 1,2-dichloroethane are mixed in a microwave reaction tube, and placed in a microwave reactor. React at 90°C to 140°C for 5min to 60min, and use thin layer chromatography (TLC) to detect that the reaction is complete; cool the product obtained in step (1) to room temperature, concentrate under pressure, and use silica gel column chromatography to separate and purify , the pure product was obtained. The method can be used to synthesize the fluorinated cyclic phosphonamide derivative, and the method has simple steps, short reaction time, high thermal energy utilization rate and high yield. |
| priorityDate | 2019-11-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 34.