http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111116575-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D417-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-02 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D417-12 |
| filingDate | 2019-12-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2021-06-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2021-06-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-111116575-B |
| titleOfInvention | 5-fluoro-2, 4-pyrimidinediamine compound and preparation and application thereof |
| abstract | The invention discloses a 5-fluoro-2, 4-pyrimidinediamine compound with a structure shown in a formula (I), a preparation method thereof and application thereof in preparing an anti-tumor medicament, wherein the anti-tumor medicament is a medicament for treating liver cancer, lung cancer or leukemia. The compound of formula (I) provided by the invention has good anti-tumor activity, and provides a foundation for new drug screening; has obvious inhibiting effect on HepG-2 cell strains, A549 cell strains and HL-60 cell strains; in addition, the invention provides a preparation method of the formula (I), which is simple and beneficial to industrial production. |
| priorityDate | 2019-12-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 104.