http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111110912-B
Outgoing Links
Predicate | Object |
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classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-507 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-227 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-025 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-22 |
filingDate | 2020-02-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2021-12-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2021-12-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-111110912-B |
titleOfInvention | Functional silk fibroin scaffold with cell response migration effect and preparation method thereof |
abstract | The invention discloses a functional silk fibroin bracket with cell response migration effect and a preparation method thereof, and the preparation method comprises the following steps: firstly, degumming, dissolving and dialyzing natural silk to obtain a silk fibroin solution; injecting the concentrated and purified silk fibroin solution into a specific mould, and freeze-drying to obtain a molded scaffold; thirdly, soaking the formed support in the iron oxide nanoparticle solution to obtain a functional component; fourthly, coating a layer of DPPC film on the inner layer and the outer layer of the support with the iron oxide nanoparticles; and fifthly, coating the PVA film on the outer layer of the support obtained in the step four, and obtaining the functional support with good stability. The scaffold prepared by the method has good cell compatibility and temperature-controlled degradability, has a remarkable cell response migration effect, can promote the repair of various tissues, and has huge application potential in the field of tissue engineering repair. |
priorityDate | 2020-02-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 97.