| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6b33dd6f3ada81a293d6202f04929e5d |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0019
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-7036
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-08 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7036
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-08 |
| filingDate |
2018-10-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_04b4037f0037c97eebd8c77d323e7ed7
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b7c98f58af29ca902979c60e5ae1601c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fc4dfb75a6247799fc627a9055817491 |
| publicationDate |
2020-05-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CN-111110627-A |
| titleOfInvention |
A kind of amikacin sulfate injection and preparation method thereof |
| abstract |
The invention discloses an amikacin sulfate injection using acetate as a buffer and a preparation method thereof. The injection contains the active ingredient amikacin sulfate, a buffer, an antioxidant and a pH adjuster. The buffering agent is acetate, and the pH range of the injection is 3.5-5.5. The advantages of the invention are that the thermal stability of the amikacin sulfate injection is improved, and the acetate is used as a buffer to effectively reduce the degradation of the amikacin sulfate during the moist heat sterilization process, thereby ensuring that the pharmaceutical preparation is Stability during transportation and storage. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111904929-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111904929-B
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-115282116-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-115282116-B |
| priorityDate |
2018-10-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |