http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111072743-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J3-005 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J3-00 |
| filingDate | 2018-10-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2022-06-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2022-06-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-111072743-B |
| titleOfInvention | Synthetic method of loteprednol etabonate intermediate |
| abstract | The invention provides a preparation method of an loteprednol etabonate intermediate, which takes cheap and easily-obtained 11 alpha-hydroxy-ADD as a starting material and obtains 17 beta carboxylic acid (a compound VII) through dehydration, Grignard, hydrolysis, oxidation, hydroxyl bromination and reduction. The invention has the advantages of easily obtained starting materials, high yield, good purity and stable process. |
| priorityDate | 2018-10-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 13.