http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111072605-B

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classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D307-79
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D493-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D209-26
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D307-79
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D493-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D209-26
filingDate 2019-12-17-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2021-11-02-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2021-11-02-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-111072605-B
titleOfInvention Preparation method of fluoroalkyl-substituted benzofuran derivative or indole derivative
abstract The invention belongs to the technical field of pharmaceutical chemical synthesis, and discloses a preparation method of a fluoroalkyl-substituted benzofuran derivative or indole derivative, which comprises the following steps: taking a 2-allyl phenol compound or a 2-allyl-aniline compound as a raw material, adding alkali, a fluoroalkyl reagent, a solvent and a photocatalyst, stirring the obtained solution under the atmosphere of illumination and nitrogen for reaction, extracting the reaction solution after the reaction is finished, removing the solvent under reduced pressure to obtain a crude product, and purifying to obtain the fluoroalkyl-substituted benzofuran derivative or indole derivative. The method for synthesizing fluoroalkyl-substituted benzofuran derivatives and indole derivatives efficiently through photocatalysis has the advantages of simplicity, easiness, mild reaction conditions, wide adaptability to substrates, high product yield and good industrial application prospect.
priorityDate 2019-12-17-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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