http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111072605-B
Outgoing Links
Predicate | Object |
---|---|
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D307-79 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D493-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D209-26 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D307-79 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D493-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D209-26 |
filingDate | 2019-12-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2021-11-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2021-11-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-111072605-B |
titleOfInvention | Preparation method of fluoroalkyl-substituted benzofuran derivative or indole derivative |
abstract | The invention belongs to the technical field of pharmaceutical chemical synthesis, and discloses a preparation method of a fluoroalkyl-substituted benzofuran derivative or indole derivative, which comprises the following steps: taking a 2-allyl phenol compound or a 2-allyl-aniline compound as a raw material, adding alkali, a fluoroalkyl reagent, a solvent and a photocatalyst, stirring the obtained solution under the atmosphere of illumination and nitrogen for reaction, extracting the reaction solution after the reaction is finished, removing the solvent under reduced pressure to obtain a crude product, and purifying to obtain the fluoroalkyl-substituted benzofuran derivative or indole derivative. The method for synthesizing fluoroalkyl-substituted benzofuran derivatives and indole derivatives efficiently through photocatalysis has the advantages of simplicity, easiness, mild reaction conditions, wide adaptability to substrates, high product yield and good industrial application prospect. |
priorityDate | 2019-12-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 58.