abstract |
The invention discloses a new green synthesis method for efficiently synthesizing C-N bonds and cyclizing quinoxaline derivatives through pure water as solvent, sulfur ylide as carbene donor, transition metal-catalyzed carbene insertion/cyclization reaction. Compared with the traditional method, the method has easy-to-obtain raw materials, simple steps, avoids the use of toxic organic solvents, is a mild, fast, simple, effective and environmentally friendly method for preparing quinoxaline parent rings, and has wide application prospect. |