| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7c273e10b5c6cf688f12411bf17de7a0 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-5377
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-165 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-165
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-5377 |
| filingDate |
2019-12-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_64916c0261b24f60fa7d1279212ef38f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d37cb745d4abc3208fcea239d260cc7f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8fbf1c35f4dcdc6292fa2b91d6434019 |
| publicationDate |
2020-04-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CN-111068055-A |
| titleOfInvention |
A combined inhibitor and application thereof |
| abstract |
A combination inhibitor comprising a specific inhibitor of histone deacetylase 8 and an inhibitor of FLT3. By using a specific inhibitor of histone deacetylase 8, the resistance mechanism of leukemia cells to upregulate the expression of histone deacetylase 8 and resist FLT3 inhibitors is eliminated, so as to more effectively treat FLT3-ITD positive acute myeloid leukemia. |
| priorityDate |
2019-12-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |