http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111057035-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D405-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D311-30 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-496 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D405-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D311-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-352 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-5377 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-453 |
| filingDate | 2019-11-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2021-10-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2021-10-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-111057035-B |
| titleOfInvention | Baicalein derivative and preparation method and application thereof |
| abstract | The invention discloses a baicalein derivative, which has the following structure: wherein R is 1 Is hydrogen, alkyl, substituted or unsubstituted aryl; r 2 Is hydrogen, halogen, alkyl, alkoxy, substituted or unsubstituted amino, substituted or unsubstituted aryl; r 3 Is oxygen or sulfur; r 4 Is a substituted or unsubstituted aryl group. The synthesis method of the baicalein derivative prepared by the invention is simple and convenient, the pollution is reduced, and experiments prove that the baicalein prepared by the inventionThe derivative can be used together with azole antifungal drugs, can improve the sensitivity of drug-resistant bacteria to azole drugs, and realizes reversal drug resistance, so that the invention provides a new way for clinical treatment of drug-resistant fungi. |
| priorityDate | 2019-11-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 108.