http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111035803-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2300-404 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2430-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2300-216 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-54 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-18 |
| filingDate | 2019-11-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2021-07-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2021-07-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-111035803-B |
| titleOfInvention | Titanium implant material with anti-infection and osseointegration promoting functions and preparation method thereof |
| abstract | The invention relates to a titanium implant material with anti-infection and bone union promoting functions and a preparation method thereof. The invention prepares hyperbranched polylysine (HBPL) by a thermal initiation one-pot method, and covalently grafts HBPL to a titanium sheet by utilizing a silane coupling agent gamma- (2, 3-epoxypropoxy) propyl trimethoxy silane (GPTMS). The hyperbranched polylysine fixed on the surface of the titanium sheet has very good bactericidal effect on gram-positive staphylococcus aureus and gram-negative escherichia coli. Meanwhile, compared with pure titanium, the material can promote the adhesion, proliferation and differentiation of osteoblasts and has no cytotoxicity. The invention has simple process flow and lower production cost, has the functions of resisting infection and promoting osseointegration on the basis of good safety, innovatively applies the hyperbranched polylysine to the field of implants, has important significance in the aspect of titanium implant modification and has good application prospect. |
| priorityDate | 2019-11-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 69.