http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111035485-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2300-252 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2300-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2300-416 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61F2210-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2420-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61F2240-001 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2420-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2420-04 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L31-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61F2-82 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L31-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L31-14 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61F2-82 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L31-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L31-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L31-08 |
| filingDate | 2019-12-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2021-12-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2021-12-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-111035485-B |
| titleOfInvention | Intravascular stent and preparation method and application thereof |
| abstract | The invention discloses a vascular stent and a preparation method and application thereof, relating to the technical field of vascular stents. The intravascular stent comprises a stent body, an inner coating, an intermediate coating and an outer coating, wherein the inner coating contains phenolic hydroxyl or quinonyl and catalytically active metal ions, the metal ions and the phenolic hydroxyl or quinonyl form coordinate bonds to be deposited on the surface of the stent body, the intermediate coating contains the phenolic hydroxyl or quinonyl but does not contain the catalytically active metal ions, and the outer coating is formed by grafting mercapto REDV on the surface of the intermediate coating. Further, there is provided a preparation method comprising placing the stent body in a solution containing a phenolic hydroxyl group or a quinone group and a catalytically active metal ion to form an inner coating layer, then placing in a solution containing catechol to form an intermediate coating layer, and grafting a thiolated REDV onto the surface of the intermediate coating layer to form an outer coating layer. The preparation method has few intermediate steps and is simple and feasible. The obtained vascular stent has the functions of anticoagulation, anti-hyperplasia and promoting endothelialization. |
| priorityDate | 2019-12-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 78.