| abstract |
An object of the present invention is to provide a modified lipase having excellent stability and reactivity at high temperatures. A modified lipase, having in the amino acid sequence of SEQ ID NO: 1, an amino acid sequence containing one or more amino acid substitutions selected from T130C-S153C, A249P, F259Y, S282P, S283Y and S300P or an amino acid sequence with the amino acid sequence Amino acid sequences showing more than 90% homology have improved reactivity and/or stability at high temperatures. |